The medication Otrivin Metered Dose Nasal Spray 0.05% is used to treat colds. One spray puff is equivalent to 0.035 mg of Xylometazoline hydrochloride, meaning that each milliliter contains 0.5 mg of this compound. This nasal spray is meant to be sprayed into the nostrils, where it constricts blood vessels and releases mucus from the throat and nose.